Evidence must be stratified
Research on cosmetic actives should distinguish in vitro experiments, animal models, ex vivo follicle work, human studies, supplier materials, and mixed-formulation evidence. Clear evidence stratification prevents mechanistic plausibility from being overstated as proven efficacy.
A differentiated research hypothesis
AIBIOOS has introduced the Nanoceria-Assisted Follicular Rejuvenation Model, connecting ROS clearance, hair follicle stem-cell protection, Wnt/β-catenin preservation, and melanocyte stem-cell protection.